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About Us

Our Mission

Research at the Baruch S. Blumberg Institute primarily focuses on understanding the pathobiology of hepatitis B virus and related diseases. Additionally, we're developing diagnostics for early detection of liver cancer and therapeutics for the cure of chronic hepatitis B. Our research extends to investigating other RNA viruses causing hepatitis and hemorrhagic fever. We're also working on developing antiviral drugs and immune modulators to treat these viral diseases. Our research is led by faculty members with complementary expertise in virology, immunology, cancer biology, chemistry and drug development, and organized into six research programs directed by senior faculty members. In concerted efforts, our faculty and research staff are committed to translate our discoveries into therapeutics for the cure of hepatitis B and other viral diseases and diagnostics for early detection and precision treatment of cancer.

Our Leadership Team

Jinhong Chang

Vice President, Drug Development

Bob Christmas

Bob Christmas

Chief Operating Officer

Ju-Tao Guo

Ju-Tao Guo, MD

Chief Scientific Officer

Randall N. Hyer

Randall N.Hyer,


Louis P. Kassa III

Chief Executive Officer

Patti McAloon

Patti McAloon

Vice President, Finance

Board of Directors

Wayne Yetter, MBA, Chair

Randall N. Hyer, MD, PhD, MPH, President

Louis P. Kassa, MPA, Secretary

Joel Rosen, Esq.

Loren Danzis, Esq.

Thomas Shenk, PhD

Honorary Directors

Jane Blumberg

Anne Blumberg Dorfman


Our Founders

Dr. Baruch S. Blumberg and Dr. Timothy Block were instrumental in the creation of the Blumberg Institute in 2003 after spending many years researching liver disease.

Dr. Baruch S. Blumberg was a renowned physician and scientist who won the Nobel Prize in Physiology or Medicine in 1976 for his discovery of the hepatitis B virus and the development of the hepatitis B vaccine. His groundbreaking work in the field of virology and immunology has had a profound impact on global health, significantly reducing the incidence of hepatitis B and related liver diseases.

Dr. Block has been instrumental in advancing the institute's mission to find cures for hepatitis B and liver cancer. His leadership and vision have been pivotal in fostering a collaborative research environment that encourages innovation and scientific breakthroughs in the field of liver disease

Core Facilities

The Baruch S. Blumberg Institute manages and is located within the Pennsylvania Biotechnology Center (PABC) in Doylestown, Pa.

Located in the center of the pharma belt between north New Jersey and Philadelphia, the PABC was named one of the most successful biotechnology incubators in the country in 2018.

The nonprofit life sciences incubator-accelerator offers state-of-the-art laboratory and office space to more than 50 biotechnology, pharmaceutical and research companies, as well as two nonprofits.

Our Location

We are located in Doylestown, PA, which offers residents and commuters a top-rated public school district, two museums, a theater, and a great mix of restaurants and shops.

Doylestown Named One Of “9 Underrated Towns” In The Nation

Doylestown is quaint, historic and thoroughly charming and home to not one, but two top-notch museums. Read more.

Doylestown: Historical treasures in a compact space

Doylestown rivals many large cities … with its world-class cultural facilities, elegant Victorian architecture and historic attractions. Read more.

What to do, eat, and see in Doylestown

Doylestown in Bucks County has a little of everything. Though it’s surrounded by newer subdivisions, there’s still open countryside, working farms, 19th-century houses, and a bustling walkable downtown. Read more.

Support US

You Can Make a Difference

Support Groundbreaking Research at the Blumberg Institute

The Blumberg Institute is at the forefront of groundbreaking research to understand the hepatitis B virus, develop better treatments, and ultimately find a cure. Our scientists also are pioneering non-invasive methods to diagnose cirrhosis and liver cancer at earlier, more treatable stages.

Despite our incredible progress, much work remains. With 300 million people worldwide living with hepatitis B and at risk for cirrhosis and liver cancer, accelerating our research is crucial.

This life-saving work depends on generous support from donors like you. Your contribution can advance our research and potentially save millions of lives.

Please consider donating today to support our vital mission.

Supporting the Next Generation of Scientists!

Your generosity empowers the Blumberg Institute, Hepatitis B Foundation and Pennsylvania Biotechnology Center to offer transformative education programs for high school students and undergraduate research fellows. These young minds work alongside top scientists and entrepreneurs, engaging in groundbreaking research that can shape their future careers in the life sciences.

Thanks to a very generous donor, the Sunrise Education Fund helps sustain and expand these impactful programs.

Your gift can put lab coats on students, ignite their passion for science, and launch their careers in the life sciences!

Donate today and be a part of their journey.